Survival of the mouse mammary tumor agent (MTA) in frozen tissue.
نویسنده
چکیده
It has been established that the mouse mam mary tumor agent (MTA), with the properties of an infectious agent or virus, will withstand filtra tion, lyophilization, and desiccation (1, 2-4, 8-10, 15). Gye (11) and Mann (12-14) advanced the theory that the agent would be liberated in its active form following freezing and would induce mammary cancer within a short time, because of its "selective infectivity" for the mammary
منابع مشابه
Host-induced changes in the mouse mammary tumor agent from transplanted tumors as determined by neutralization studies.
The mouse mammary tumor agent (MTA), normally transferred in the milk of females of cancerous strains, has the properties of an infectious agent or virus (1, 8-6). Antisera produced against agent-containing mouse mammary tissues, either normal or cancerous, in rabbits, rats, or guinea pigs have been found to neutralize the MTA in vivo and in vitro (1, 15, 24). The studies to be reported (8) wer...
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cause and that this, in mammals as in birds, is a virus.― Mann (33—35)injected frozen spontaneous and transplanted mammary cancers and explained the development of tumors on the basis that the mam mary tumor milk agent-virus was liberated in its active form following freezing, since mammary tu mors arose at the site of injection of the suspended frozen tumor-mince. The tumors developed as r...
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عنوان ژورنال:
- Cancer research
دوره 18 6 شماره
صفحات -
تاریخ انتشار 1958